Fiziksel Yaralanmalar ve Protein Metabolizması

Abstract

Physical injury causes damage to and lose of body proteins. The metabolic reaction to injury consist of variety of chemical and physiological changes which involve protein, carbohydtare, fat, water, vitamin, endocrine and elektrolyte metabolism in almost every organ of the body . Although ali metabolites seem to be involved, the extent and duration of their involvement vary, most of the disturbances are short but protein changes prolonged. Mainly, plasma proteins, gastrointestinal system, Jiver, kidney and adrenal glands are affected. The biological significance of increased nitrogen lo ss after in ju ry continues to remain uncertain. In severe cases, nitrogen excretion in the urine as urea is the highest in the acute catabol ic phase just after injury. The loss reaches a peak at the third and fourth day after injury. In general, the lcss is proportional to the previous and present level of protein intake, and the magnitude of the injury. In other words, if protein is not given in excess in the diet, the protein utilization in the body is more economlcal and excess heat production could be prevented.