Romatoid Artritli Hastalarda Plazma Selenyum Seviyeleri

Abstract

In o rd e r to investigate whether selenium (Se) is an important factor in the pathogenesis of rheumatoid arthritis (RA), the plasma Se levels were determined in RA patients and healthy controls. Plasma Se levels in 60 patients were found to be significantly lower than those in 60 normal, healthy controls (p<0.001). Similar significant differences were determined in sex-matched comparisons between patients and controls (p<0.001); but, there was no significant difference in plasma Se levels in sex-matched comparisons in both groups (p>0.05). In conclusion, Se supplementation might lead to clinical improvement in patients with RA.