Evaluation o f Nutritional Status and Related Biochemical Flndings Among Children who Received Bone Marrow Transplantation

Abstract

This stııdy was conducted to determine the varicıtions of parameters t hat reflect the nııtritional statııs o f 5 patients who were between 3.5 t o 10.0 years ofage and received bone marrow transplantation (BMT) in Hacettepe University Medical Faculty Ihsan Doğramacı Children s Hospital BMT Unit. Patients were examined for clinical parameters daily, starting 10 days before the transplantation through the first 30 days following it and their energy, protein, zinc and magnesiıım intakes were calculated. As well as hematologic values, their serum zinc, magnesium, albıımin, prealbıımin, retinol binding protein (RBP) levels were also examined at the 10îh and l st day preceeding the transplantation and 8th, 20th, 30th and 70th days following it. Total energy and protein intake through foods, enteral formıılas and by parenteral ways declined during the fırst 20 days after transplantation. This decrease, however was not statistically signifıcant. After being discharged from the hospital at the 70th day following the BMT, laboratory determinations were made again without taking their food consumptions. Serum zinc and magnesium levels continııed to until the 8th and 20th days respectively and this decrease was also observed on the 30th and 70lh days control visits. Serum albumin, prealbıımin and RBP levels decreased dııring the fırst 8 days after the transplantation hovvever they started to rise there after. Althoııgh the number of patients were small, it is appererıt that, serum prealbıımin and RBP levels rejlect the cluınges in the nutritional status of patients in a shorter period than albumin.