Plasma Lipid Profiles and Mutagenicity on Some Tissues in Rats Fed with Repeateadly Used Deep Fat Frying

Abstract

In this study, the effect ofdeep frying fats on the plasma lipid profıles and the possible toxic effects on some tissues in rats w er e investigated. The rats were on a special diet for 5 weeks consisted of sunflower oil which was used 5,10,15 times for deep-fat frying of potatoes. In the control group, the sunflovver oil was directly added to the diet without being used in frying. The diet that was prepared according to the healthy feeding principles providing the 56% from carbohydrate, 15% from protein and 29% from fat of the total energy. At the end of the 5th week blood samples for the plasma lipid profiles and tissue samples from aorta, colon, kidney and liverfor assessment of mutagenicity w er e obtained. Itı each groups, rats have gained similar amounts ofweight. The plasma trigliseride levels were similar in distribution. The re w er e statistically significaııt decrease in plasma total cholesterol, HDL-cholesterol and LDL-cholesterol levels among the groups. There w er e no pathological changes in the colonic or renal tissues and no atherogenic changes in the aorta. However there were significant cellular changes in the liver that correlate with the increase in the use of frying frequency of the fats.