Assessment of Anthropometric Measurements and Biochemical Findings in Patients with Insulin Resistance

Abstract

Aim: The aim of this study was to assess the anthropometric measurements and biochemical findings in patients with insulin resistance. Subjects and Methods: This study was conducted on 53 female patients, aged 30-50 years, for the first time insulin resistance diagnosed, having no disease other than hyperlipidemia, body mass index (BMI) between 30-40 kg/m2 admitted to Haydarpaşa Numune Education and Research Hospital Internal Medicine Outpatient Clinic, between October 2011 and April 2012. A questionaire on personal and disease information was applied to these patients. Biochemical parameters were examined, some anthropometric measurements were taken, and HOMA-IR (Homeostatis Model Assessment-Insulin Resistance) values were calculated. Results: It was found that BMI, fat mass, percentage of fat, waist circumference of patients were above normal levels. Triglycerides, high density lipoprotein (HDL) cholesterol, plasma fasting glucose, postprandial glucose, fasting insulin and postprandial insulin levels were within normal limits; low density lipoprotein (LDL) cholesterol and very low density lipoprotein (VLDL) cholesterol levels were close to upper limits; total cholesterol level was at upper limit; HOMA-IR levels were above normal. Conclusion: In patients with insulin resistance, BMI, body fat, fat percentage, waist circumference, HOMA-IR values were higher; fasting glucose, postprandial glucose, fasting insulin, postprandial insulin, blood levels of fasting triglycerides, total cholesterol, HDL-cholesterol, LDL-cholesterol, VLDL-cholesterol levels were found to be at normal levels. So calculation of HOMA-IR in obese patients, patients with insulin resistance will be captured in the early period.