The Role of Some Anthropometric and Biochemical Indices as Predictors of Non-Alcoholic Fatty Liver Disease

Abstract

Aim: This study has been conducted to evaluate the descriptive performance of anthropometric and biochemical indexes in non-alcoholic fatty liver disease (NAFLD) screening in the population.

Subjects and Method: This study has been conducted between March and July 2021 on a total of 104 individuals of whom 52 were NAFLD patients and 52 were control subjects aged 19-64, who had referred to the Diet Polyclinic of a state hospital. Anthropometric measurements and some biochemical findings from last month it has been recorded in the questionnaire applied to the participants. The indexes used in the study (Visceral Adiposity Index-VAI, Framingham Steatosis Index-FSI, Lipid Accumulation Product-LAP) has been calculated by using the anthropometric measurements and biochemical findings of the individuals.

Results: For both genders, all indexes used in the study it has been found significantly higher in the case group compared to the control group (p<0.05). According to logistic regression analysis, has not been observed significant relationship between VAI, Framingham steatosis index, lipid accumulation product and risk of NAFLD in man (p>0.05). According to ROC analysis, it has been found that lipid accumulation product in females and hepatic steatosis index in males produce the highest rate of accuracy for ultrasonographic NAFLD diagnosis.

Conclusion: The use of lipid accumulation product and hepatic steatosis index may be beneficial for a simple and quick identification of patients suspected for NAFLD who need advanced examination and treatment.