Depression and Vitamin D

Abstract

For long years vitamin D was known with its function on bone protection. However, in recent years it has been stated that there are lots of extra-bone effects. Studies show that vitamin D deficiency may have a role in the etiology of mood disorders. Discovering vitamin D receptors (VDR) in the multiple parts of the brain supports this relationship. Epidemiological studies also show that serum 25-hydroxy vitamin D levels are low in people with depression. In this review article, the relationship between vitamin D and depression was reviewed using the current literature.