Effects of Resveratrol on Cardiovascular Diseases

Abstract

Cardiovascular diseases is one of the leading causes of mortality in the world. Alternative pharmacotherapy methods using natural nutraceuticals are very promising in preventing cardiovascular diseases and increasing the effect of the treatments applied. One of these natural compounds that are thought to potentially help to treat cardiovascular diseases and prevent their development is resveratrol. Bioactive dietary components such as resveratrol are thought to have more than one cellular target. Therefore, they may have many effects including cardioprotective, antioxidant, anticancer, anti-inflammatory, antidyslipidemic and antidiabetic. Resveratrol (trans-3,4’,5 trihydroxystylbene, RES) naturally found in various plants is a non-flavonoid polyphenol belonging to the stilbenoid group produced in response to fungal attack or injury. It is found in a variety of foods such as grapes, red wine, strawberries and peanuts. In this review, it is aimed to present the basic research published recently on the protective cardiovascular effects of resveratrol. The revealed implications are intended to contribute to the development of new clinical / therapeutic strategies in patients.