Effect of Obesity on Nutritional Status and Biochemical Parameters in Maintenance Hemodialysis Patients

Abstract

Aim: Conversely the general population, high Body Mass Index (BMI) that is a marker of overnutrition and hypercholesterolemia associated with improving poor clinical outcome and increasing survival rate in maintenance hemodialysis (HD) patients. The aim of this cross-sectional study was to investigate the effects of obesity on biochemical parameters and nutritional status in 15 normal weight and 15 overweight/obese HD patients. Subjects and Methods: 30 HD patients divided into two groups according to body mass index: normal weight (BMI 18.5-24.9 kg/ m²) and overweight/obese (BMI≥25 kg/m²). Blood samples were collected before the dialysis session and the percentage of body fat was assessed by using bioelectric impedance analysis (BIA) after dialysis session. Anthropometric measurements, three days dietary recalls were collected by face to face and subjective global assessment (SGA) was applied to each HD patient. Results: Body fat mass percentage with BIA was found higher in both male and female overweight/obese patients. Triceps skinfold thicknesses (TSF) and mid upper arm circumferences (MUAC) were not different in two groups in males whereas, in overweight/obese female HD patients TSF and MUAC were higher (p<0.05). Moreover, total cholesterol, triglyceride, LDL-cholesterol, HDL-cholesterol, VLDL-cholesterol levels also were found higher in overweight/obese patients (p<0.05). According to dietary recalls mean energy, macronutrients, vitamins and minerals, cholesterol intakes were similar in each group (p>0.05). Conclusion: In the view of high BMI and obesity could reduce morbidity and mortality risk in HD patients. So the maintaince of body weight and body fat mass were found to be important for reducing malnutrition risks and outcomes.