Evaluation of Some Risk Factors on Premenopausal Breast Cancer Women: A Case-Control Study

Abstract

Aim: This study was carried out to determine some risk factors of breast cancer in premenopausal women. Subjects and Methods: This study was conducted on 70 premenopausal female individuals with newly diagnosed breast cancer who had been operated or not and applied to Hacettepe University Oncology Hospital between November 2013-July 2014, and on equal number of healthy adult female individuals who were paired in order to ensure the standardization in age, gender and menopausal status. Results: When individuals who have their first child before the age of 20 were compared with the individuals who have their first child after the age of 30, their breast cancer risk was determined to be lower by 81%. Similarly breast cancer risk is decreased 8% for each first birth unit. There is an association between breast-feeding and breast cancer risk and women who had breastfed and not were compared, their breast cancer risk was determined to be 2.2 times higher and statistically significant difference was determined. When the cumulative smoking status of the individuals participating in this study is examined the patient group showed higher smoking rate than the control group. Conclusion: By taking into consideration of modifiable factors and identification of risk groups may contribute to the development of prevention strategies in decreasing breast cancer incidence.